Barenblatt e. a. introduced a fluid model for groundwater flow in fissurised porous media. The system consists of two diffusion equations for the groundwater levels in, respectively, the porous bulk and the system of cracks. The equations are coupled by a fluid exchange term. Numerical evidence suggests that the penetration depth of the fluid increases dramatically due to the presence of cracks and that the smallness of certain parameter values play a key role in this phenomenon. In the present paper we give precise estimates for the penetration depth in terms of the smallness of some of the parameters.
The "effective geometry" formalism is used to study the
perturbations of a perfect barotropic Newtonian self-gravitating
rotating and compressible fluid coupled with gravitational
backreaction. The case of a uniformly rotating polytrope
with index $n=1$ is investigated, due to its analytical tractability.
Special attention is devoted to the geometrical
properties of the underlying background acoustic metric, focusing
in particular on null geodesics as well as on the analog
light cone structure.
KerrSchild metrics have been introduced as a linear superposition of the flat spacetime
metric and a squared null-vector field, say k, multiplied by some scalar function, say
H. The basic assumption which led to Kerr solution was that k be both geodesic and
shearfree. This condition is relaxed here and KerrSchild Ansatz is revised by treating
KerrSchild metrics as exact linear perturbations of Minkowski spacetime. The scalar
function H is taken as the perturbing function, so that Einsteins field equations are
solved order-by-order in powers of H. It turns out that the congruence must be geodesic
and shearfree as a consequence of third- and second-order equations, leading to an
alternative derivation of Kerr solution.
Bini D
;
C Cherubini
;
S Filippi
;
A Gizzi
;
P E Ricci
Spiral waves appear in many different contexts: excitable biological
tissues, fungi and amoebae colonies, chemical reactions, growing crystals, fluids
and gas eddies as well as in galaxies. While the existing theories explain the
presence of spirals in terms of nonlinear parabolic equations, in this paper it
is shown that self-sustained spiral wave regime is already present in the linear
heat operator, in terms of integer Bessel functions of complex argument. Such
solutions, even if commonly not discussed in the literature because diverging at
spatial infinity, play a central role in the understanding of the universality of
spiral process. As an example we have studied how in nonlinear reaction-diffusion
models the linear part of the equations determines the wave front appearance
while nonlinearities are mandatory to cancel out the blowup of solutions. The
spiral wave pattern still requires however at least two cross diffusing species to be
physically realized.
We consider splitting methods for the numerical integration of separable non-autonomous differential equations. In recent years, splitting methods have been extensively used as geometric numerical integrators showing excellent performances (both qualitatively and quantitatively) when applied on many problems. They are designed for autonomous separable systems, and a substantial number of methods tailored for different structures of the equations have recently appeared. Splitting methods have also been used for separable non-autonomous problems either by solving each non-autonomous part separately or after each vector field is frozen properly. We show that both procedures correspond to introducing the time as two new coordinates. We generalize these results by considering the time as one or more further coordinates which can be integrated following either of the previous two techniques. We show that the performance as well as the order of the final method can strongly depend on the particular choice. We present a simple analysis which, in many relevant cases, allows one to choose the most appropriate split to retain the high performance the methods show on the autonomous problems. This technique is applied to different problems and its performance is illustrated for several numerical examples.
This work deals with infinite horizon optimal growth models and uses the results in the Mercenier and Michel (1994a) paper as a starting point. Mercenier and Michel (1994a) provide a one-stage Runge-Kutta discretization of the above-mentioned models which preserves the steady state of the theoretical solution. They call this feature the "steady-state invariance property". We generalize the result of their study by considering discrete models arising from the adoption of s-stage Runge-Kutta schemes. We show that the steady-state invariance property requires two different Runge-Kutta schemes for approximating the state variables and the exponential term in the objective function. This kind of discretization is well-known in literature as a partitioned symplectic Runge-Kutta scheme. Its main consequence is that it is possible to rely on the well-stated theory of order for considering more accurate methods which generalize the first order Mercenier and Michel algorithm. Numerical examples show the efficiency and accuracy of the proposed methods up to the fourth order, when applied to test models.
In this paper, we start a general study on relaxation hyperbolic systems which
violate the Shizuta-Kawashima ([SK]) coupling condition. This investigation is
motivated by the fact that this condition is not satisfied by various physical sys-
tems, and almost all the time in several space dimensions. First, we explore the role
of entropy functionals around equilibrium solutions, which may not be constant,
proposing a stability condition for such solutions. Then we find strictly dissipa-
tive entropy functions for one dimensional 2 × 2 systems which violate the [SK]
condition. Finally, we prove the existence of global smooth solutions for a class of
systems such that condition [SK] does not hold, but which are linearly degenerated
in the non-dissipative directions.
relaxation systems
dissipative hyperbolic problems
weak coupling conditions
Quantifying trace gas emissions and the influence of surface exchange processes on the atmosphere is a necessary step towards the control of global greenhouse gas emissions and reliability of air quality models. This paper proposes a procedure based on the mass balance method and implemented on highly resolved aircraft data. It allows one to estimate surface exchanges on areas of several km2 and heterogeneous features exploiting the characteristics of convective boundary layer during steady state conditions that permit the estimation of emission/absorption terms as functions of advective fluxes only. A nonparametric approach is adopted and the fluxes on the surface of a virtual box surrounding the area of interest are reconstructed on the basis of scalar densities and wind vectors using Shepard functions. Two different techniques are also proposed to face lack of data on the top surface of the box. The method has been applied to experimental data coming from measurement campaigns on two different sites. It provides realistic estimates of the CO2 emission/absorption in the considered areas that are in good agreement with CO2 fluxes evaluated by Airborne Eddy Covariance and confirm the suitability of the proposed approach for the assessment of turbulent exchange of trace gases by composite landscapes. Uncertainties on the estimated emissions due to both propagation of the experimental error and interpolation have been quantified by bootstrap analysis as 6%.
This letter investigates the possibility of removing noise in correspondence to jump discontinuities using the sorted copy of the signal. It will be proved that sorting makes noise predictable so that it can be reproduced and subtracted from the sorted noisy signal. It will be also shown that the proposed method can substitute for the edge preserving term into an anisotropic diffusion scheme, gaining in terms of mean square error, edge preservation and computational effort.
Transconjunctival suture- less 25-gauge versus 20-gauge standard vitrectomy: correlation between corneal topography and ultrasound biomicroscopy measurements of sclerotomy sites
We present a new approach to the study of the immune system that combines techniques of systems biology with
information provided by data-driven prediction methods. To this end, we have extended an agent-based simulator of the
immune response, C-IMMSIM, such that it represents pathogens, as well as lymphocytes receptors, by means of their amino
acid sequences and makes use of bioinformatics methods for T and B cell epitope prediction. This is a key step for the
simulation of the immune response, because it determines immunogenicity. The binding of the epitope, which is the
immunogenic part of an invading pathogen, together with activation and cooperation from T helper cells, is required to
trigger an immune response in the affected host. To determine a pathogen's epitopes, we use existing prediction methods.
In addition, we propose a novel method, which uses Miyazawa and Jernigan protein-protein potential measurements, for
assessing molecular binding in the context of immune complexes. We benchmark the resulting model by simulating a
classical immunization experiment that reproduces the development of immune memory. We also investigate the role of
major histocompatibility complex (MHC) haplotype heterozygosity and homozygosity with respect to the influenza virus
and show that there is an advantage to heterozygosity. Finally, we investigate the emergence of one or more dominating
clones of lymphocytes in the situation of chronic exposure to the same immunogenic molecule and show that high affinity
clones proliferate more than any other. These results show that the simulator produces dynamics that are stable and
consistent with basic immunological knowledge. We believe that the combination of genomic information and simulation
of the dynamics of the immune system, in one single tool, can offer new perspectives for a better understanding of the
immune system.
ImmunoGrid: towards agent-based simulations of the human immune system at a natural scale.
HallingBrown
;
Pappalardo F
;
Rapin N
;
Zhang P
;
Alemani D
;
Emerson A
;
Castiglione F
;
Doroux P
;
Penisi M
;
Miotto O
;
Churchill D
;
Rossi E
;
Moss DS
;
Sansom CE
;
Bernaschi M
;
Lefranc MP
;
Brunak S
;
Motta S
;
Lollini PL
;
Basford K
;
V Brusic