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2023 Articolo in rivista open access

Climate Change Effects on Carbonation Process: A Scenario-Based Study

Bretti ; Gabriella ; Ceseri ; Maurizio

Using a mathematical model of concrete carbonation that describes the variation in porosity as a consequence of the involved chemical reactions, we both validated and calibrated the related numerical algorithm of degradation. Once calibrated, a simulation algorithm was used as a forecasting tool for predicting the effects on the porosity of concrete exposed to increasing levels of CO2 emissions, as well as to rising temperatures. Taking into account future projections of environmental modifications deriving from climate changes, some scenarios were produced numerically by the mathematical algorithm that showed the effects of different pollution levels and global warming on the porosity of Portland cement in a time window of years. Finally, a theoretical study on the effects of pollution levels on the carbonation constant determining the advancement in the carbonation front was carried out for the analyzed scenarios.

concrete carbonation reaction and diffusion models climate changes model parameter estimation mathematical algorithms
2023 Articolo in rivista metadata only access

Computing Gaussian quadrature rules with high relative accuracy

The computation of n-point Gaussian quadrature rules for symmetric weight functions is considered in this paper. It is shown that the nodes and the weights of the Gaussian quadrature rule can be retrieved from the singular value decomposition of a bidiagonal matrix of size n/2. The proposed numerical method allows to compute the nodes with high relative accuracy and a computational complexity of O(n). We also describe an algorithm for computing the weights of a generic Gaussian quadrature rule with high relative accuracy. Numerical examples show the effectiveness of the proposed approach.

Gaussian quadrature rule
2023 metadata only access

LENTO: Unpredictable Latency-based continuous authEntication for Network inTensive IoT envirOnments

Mohammed AlSadi ; Roberto Di Pietro ; Flavio Lombardi ; Matteo Signorini

Started as a hyped technology a few years ago, IoT is now a reality providing sensing and computing capabilities from SCADA systems to households. At their core, IoT devices connect to the outside world to share sensed or computed data. However, the sensitivity and privacy of shared data has made access management a stringent need also for the IoT. In particular, continuous authentication could solve a few security issues, like session hijacking, via checking device legitimacy for each exchanged message and preventing attackers from pretending their actions came from authenticated devices. To date, device-to-device (D2D) continuous authentication still relies on tokens/certificates or devices' fingerprints such as battery levels or location. The cited solutions, while being not always implementable on resource constrained devices, provide low-entropy and thus sporting a non negligible probability of being guessable during impersonation attacks. In this paper, we overcome the above limitations with LENTO: unpredictable Latency-based continuous authEntication for Network inTensive IoT envirOnments. In addition to a thorough analysis, we also offer experimental validation of our proposal. We have deployed LENTO as an additional authentication module of the well-known NextCloud platform, and we have performed an extensive experimental campaign. Collected results confirm our working hypothesis. Network delays can be exploited as random seeds in continuous authentication protocols as they provide as much entropy as standard approaches. To the best of our knowledge, our approach is the first continuous authentication protocol relying purely on the network characteristics, regardless of the underneath computing base trustworthiness. Given the minimal overhead introduced by our solution, it provides continuous authentication even for those devices that cannot afford to run (defacto) standard protocols. As such, LENTO could be retrofitted, offering enhanced security to a plethora of nowadays unsecured devices.

Continuous authentication Internet of Things (IoT) Security Latency Cloud Network
2023 Articolo in rivista restricted access

The Knapsack Problem with forfeit sets

D'Ambrosio Ciriaco ; Laureana Federica ; Raiconi Andrea ; Vitale Gaetano

This work introduces a novel extension of the 0/1 Knapsack Problem in which we consider the existence of so-called forfeit sets. A forfeit set is a subset of items of arbitrary cardinality, such that including a number of its elements that exceeds a predefined allowance threshold implies some penalty costs to be paid in the objective function value. A global upper bound on these allowance violations is also considered. We show that the problem generalizes both the Knapsack Problem with conflicts among item pairs and the Knapsack Problem with forfeit pairs, that have been previously introduced in the literature. We present a polynomial subcase by proving the integrality of its LP relaxation polytope and, we introduce three heuristic approaches, namely a constructive greedy, an algorithm based on the recently introduced Carousel Greedy paradigm and a hybrid Memetic/Carousel Greedy algorithm. Finally, we validate the performances for the proposed algorithms on a set of benchmark instances that consider both random and correlated data.

Knapsack Problem Conflicts Forfeit sets Carousel Greedy Memetic algorithm
2023 Articolo in rivista open access

The IAS-MEEG Package: A Flexible Inverse Source Reconstruction Platform for Reconstruction and Visualization of Brain Activity from M/EEG Data

Calvetti Daniela ; Pascarella Annalisa ; Pitolli Francesca ; Somersalo Erkki ; Vantaggi Barbara

We present a standalone Matlab software platform complete with visualization for the reconstruction of the neural activity in the brain from MEG or EEG data. The underlying inversion combines hierarchical Bayesian models and Krylov subspace iterative least squares solvers. The Bayesian framework of the underlying inversion algorithm allows to account for anatomical information and possible a priori belief about the focality of the reconstruction. The computational efficiency makes the software suitable for the reconstruction of lengthy time series on standard computing equipment. The algorithm requires minimal user provided input parameters, although the user can express the desired focality and accuracy of the solution. The code has been designed so as to favor the parallelization performed automatically by Matlab, according to the resources of the host computer. We demonstrate the flexibility of the platform by reconstructing activity patterns with supports of different sizes from MEG and EEG data. Moreover, we show that the software reconstructs well activity patches located either in the subcortical brain structures or on the cortex. The inverse solver and visualization modules can be used either individually or in combination. We also provide a version of the inverse solver that can be used within Brainstorm toolbox. All the software is available online by Github, including the Brainstorm plugin, with accompanying documentation and test data.

Bayesian framework Brain activity reconstruction Conditionally Gaussian prior Iterative Krylov solver Sensitivity weighting Sliced visualization
2023 Articolo in rivista metadata only access

Modeling dual drug delivery from eluting stents: the influence of non-linear binding competition and non-uniform drug loading

S Salvi ; A Jain ; G Pontrelli ; S McGinty

Objective There is increasing interest in simultaneous endovascular delivery of more than one drug from a drug-loaded stent into a diseased artery. There may be an opportunity to obtain a therapeutically desirable uptake profile of the two drugs over time by appropriate design of the initial drug distribution in the stent. Due to the non-linear, coupled nature of diffusion and reversible specific/non-specific binding of both drugs as well as competition between the drugs for a fixed binding site density, a comprehensive numerical investigation of this problem is critically needed. Methods This paper presents numerical computation of dual drug delivery in a stent-artery system, accounting for diffusion as well as specific and non-specific reversible binding. The governing differential equations are discretized in space, followed by integration over time using a stiff numerical solver. Three different cases of initial dual drug distribution are considered. Results For the particular case of sirolimus and paclitaxel, results show that competition for a limited non-specific binding site density and the significant difference in the forward/backward reaction coefficients play a key role in determining the nature of drug uptake. The nature of initial distribution of the two drugs in the stent is also found to influence the binding process, which can potentially be used to engineer a desirable dual drug uptake profile. Conclusions These results help improve the fundamental understanding of endovascular dual drug delivery. In addition, the numerical technique and results presented here may be helpful for designing and optimizing other drug delivery problems as well.

dual drug delivery mathematical modelling binding stent
2023 Articolo in rivista open access

Image Scaling by de la Vallée-Poussin Filtered Interpolation

We present a new image scaling method both for downscaling and upscaling, running with any scale factor or desired size. The resized image is achieved by sampling a bivariate polynomial which globally interpolates the data at the new scale. The method's particularities lay in both the sampling model and the interpolation polynomial we use. Rather than classical uniform grids, we consider an unusual sampling system based on Chebyshev zeros of the first kind. Such optimal distribution of nodes permits to consider near-best interpolation polynomials defined by a filter of de la Vallée-Poussin type. The action ray of this filter provides an additional parameter that can be suitably regulated to improve the approximation. The method has been tested on a significant number of different image datasets. The results are evaluated in qualitative and quantitative terms and compared with other available competitive methods. The perceived quality of the resulting scaled images is such that important details are preserved, and the appearance of artifacts is low. Competitive quality measurement values, good visual quality, limited computational effort, and moderate memory demand make the method suitable for real-world applications.

Image downscaling Image upscaling de la Vallée-Poussin interpolation Chebyshev nodes
2023 Articolo in rivista open access

Parallel Sparse Computation Toolkit

P D'Ambra ; F Durastante ; S Filippone

This paper presents a new software framework for solving large and sparse linear systems on current hybrid architectures, from small servers to high-end supercomputers, embedding multi-core CPUs and Nvidia GPUs at the node level. The framework has a modular structure and is composed of three main components, which separate basic functionalities for managing distributed sparse matrices and executing some sparse matrix computations involved in iterative Krylov projection methods, eventually exploiting multi-threading and CUDA-based programming models, from the functionalities for setup and application of different types of one-level and multi-level algebraic preconditioners.

Linear solvers Algebraic preconditioners HPC
2023 Abstract in Atti di convegno metadata only access

Numerical simulation of a compressible gas flow in porous media bioremendiation

In a subsoil bioremediation intervention air or oxygen is injected in the polluted region and then a model for unsaturated porous media it is required, based on the theory of the dynamics of multiphase fluids in porous media. In order to optmize the costs of the intervention it is useful to consider the gas as compressible and this fact introduces nonlinearity in the mathematical model. The physical problem is described by a system of equations and the unknowns are: pollutant; bacteria concentration; oxygen saturation and oxygen pressure. Then, by algebraic manipulations, the model is reduced a to a nonlinear system of partial differential equations describing: oxygen saturation, oxygen density and bacteria concentration. For the proposed model, the results of some simulation experiments performed using COMSOL Multiphysics will be shown.

porous media subsoil bioremediation mathematical models
2023 Abstract in rivista open access

Modelling sea ice and melt ponds evolution

We present a mathematical model describing the evolution of sea ice and meltwater during summer. The system is described by two coupled partial differential equations for the ice thickness h(x,t) and pond depth w(x,t) fields. The model is similar, in principle, to the one put forward by Luthije et al. (2006), but it features i) a modified melting term, ii) a non-uniform seepage rate of meltwater through the porous ice medium and a minimal coupling with the atmosphere via a surface wind shear term, ?s (Scagliarini et al. 2020). We test, in particular, the sensitivity of the model to variations of parameters controlling fluid- dynamic processes at the pond level, namely the variation of turbulent heat flux with pond depth and the lateral melting of ice enclosing a pond. We observe that different heat flux scalings determine different rates of total surface ablations, while the system is relatively robust in terms of probability distributions of pond surface areas. Finally, we study pond morphology in terms of fractal dimensions, showing that the role of lateral melting is minor, whereas there is evidence of an impact from the initial sea ice topography.

sea-ice melt ponds wind shear heat flux probability distribution surface ablation
2023 Curatela di Atti di convegno open access

IMACS2023 Book of Abstracts of IMACS2023

This booklet contains all the abstracts of the results which are going to be presented at the IMACS World Congress taking place in Rome at theEngineering Faculty of University 'La Sapienza', September 11-15, 2023.This is the 21st one in a series of World Conferences whose complete list goes back to 1955 and covered the whole continents. The subsequent World Conferences, usually, take place every three years. Unfortunately, due to the COVID pandemics, IMACS2023, initially scheduled in 2020, had to be postponed also in order to follow the spirit of the IMACS World Conference which prescribes to gather scientists in presence from all over the world. So, in the present occasion, the whole participants are expected to convene in Rome for exchanging their works, ideas and experiences.This Book of Abstracts, reflecting the Congress structure, is organized in sections: Keynote Lectures, General Session, Mini-symposia, Special Sessions and Posters. According to the IMACS philosophy, different aspects of applied mathematics are represented with a special interest towards the numerical methods and solutions.

Applied Mathematics Scientific Computing Artificial Intelligence
2023 Software metadata only access

jewel: Graphical Models Estimation from Multiple Sources

Estimates networks of conditional dependencies (Gaussian graphical models) from multiple classes of data (similar but not exactly, i.e. measurements on different equipment, in different locations or for various sub-types). Package also allows to generate simulation data and evaluate the performance. Implementation of the method described in Angelini, De Canditiis and Plaksienko (2022) <doi:10.3390/math10213983>.

Graphical Model Estimation Network Group Lasso penalty
2023 Articolo in rivista restricted access

A resting state EEG study on depressed persons with suicidal ideation

Amico Francesco ; De Canditiis Daniela ; Castiglione Filippo ; Pascarella Annalisa ; Venerelli Noemi ; Fagan V ; Yek H ; Brophy Justin

Background: Major Depressive Disorder (MDD) is a psychiatric illness that is often associated with potentially life -threatening physiological changes and increased risk for suicidal behavior. Electroencephalography (EEG) research suggests an association between depression and specific frequency imbalances in the frontal brain re-gion. Further, while recently developed technology has been proposed to simplify EEG data acquisition, more research is still needed to support its use in patients with MDD.Methods: Using the 14-channel EMOTIV EPOC cap, we recorded resting state EEG from 15 MDD patients with suicidal ideation (SI) vs. 12 healthy controls (HC) to investigate putative power spectral density (PSD) between -group differences at the F3 and F4 electrode sites. Specifically, we explored 1) between-group alpha power asymmetries (AA), 2) between-group differences in delta, theta, alpha and beta power, 3) correlations between PSD data and scores in the Beck's Depression Inventory-II (BDI-II), Beck's Anxiety Inventory (BAI), Reasons for Living Inventory (RFL), and Self-Disgust Questionnaire (SDS).Results: When compared to HC, patients had higher scores on the BAI (p = 0.0018), BDI-II (p = 0.0001) or SDS (p = 0.0142) scale and lower scores in the RFL (p = 0.0006) scale. The PSD analysis revealed no between-group difference or correlation with questionnaire scores for any of the measures considered.Conclusions: The present study could not confirm previous research suggesting frequency-specific anomalies in depressed persons with SI but might suggest that frontal EEG imbalances reflect greater anxiety and negative self -referencing. Future studies should confirm these findings in a larger population sample.

Electroencephalogram EEG Depression Anxiety Suicidal ideation Emotiv epoc
2023 Articolo in rivista restricted access

On the probability of (falsely) connecting two distinct components when learning a GGM

De Canditiis Daniela ; Turdo Marika

In this paper, we extend the result on the probability of (falsely) connecting two distinct components when learning a GGM (Gaussian Graphical Model) by the joint regression based technique. While the classical method of regression based technique learns the neighbours of each node one at a time through a Lasso penalized regression, its joint modification, considered here, learns the neighbours of each node simultaneously through a group Lasso penalized regression.

GGM inference Lasso group Lasso
2023 Articolo in rivista restricted access

Learning binary undirected graph in low dimensional regime

Given a random sample drawn from a Multivariate Bernoulli Variable (MBV), we consider the problem of estimating the structure of the undirected graph for which the distribution is pairwise Markov and the parameters' vector of its exponential form. We propose a simple method that provides a closed form estimator of the parameters' vector and through its support also provides an estimate of the undirected graph associated with the MBV distribution. The estimator is proved to be asymptotically consistent but it is feasible only in low-dimensional regimes. Synthetic examples illustrate its performance compared with another method that represents state of the art in literature. Finally, the proposed procedure is used to analyze a data set in the pediatric allergology area showing its practical efficiency.

MBV Graphical model inference binary data analysis
2023 Articolo in rivista open access

Predictive Maintenance of Pins in the ECD Equipment for Cu Deposition in the Semiconductor Industry

Amato, Umberto ; Antoniadis, Anestis ; De Feis, Italia ; Fazio, Domenico ; Genua, Caterina ; Gijbels, Irène ; Granata, Donatella ; La Magna, Antonino ; Pagano, Daniele ; Tochino, Gabriele ; Vasquez, Patrizia

Nowadays, Predictive Maintenance is a mandatory tool to reduce the cost of production in the semiconductor industry. This paper considers as a case study a critical part of the electrochemical deposition system, namely, the four Pins that hold a wafer inside a chamber. The aim of the study is to replace the schedule of replacement of Pins presently based on fixed timing (Preventive Maintenance) with a Hardware/Software system that monitors the conditions of the Pins and signals possible conditions of failure (Predictive Maintenance). The system is composed of optical sensors endowed with an image processing methodology. The prototype built for this study includes one optical camera that simultaneously takes images of the four Pins on a roughly daily basis. Image processing includes a pre-processing phase where images taken by the camera at different times are coregistered and equalized to reduce variations in time due to movements of the system and to different lighting conditions. Then, some indicators are introduced based on statistical arguments that detect outlier conditions of each Pin. Such indicators are pixel-wise to identify small artifacts. Finally, criteria are indicated to distinguish artifacts due to normal operations in the chamber from issues prone to a failure of the Pin. An application (PINapp) with a user friendly interface has been developed that guides industry experts in monitoring the system and alerting in case of potential issues. The system has been validated on a plant at STMicroelctronics in Catania (Italy). The study allowed for understanding the mechanism that gives rise to the rupture of the Pins and to increase the time of replacement of the Pins by a factor at least 2, thus reducing downtime.

semiconductors; Predictive Maintenance; image processing; optical sensor
2023 Editoriale, Commentario, Contributo a Forum in rivista open access

Editorial: Quantification of immunological memory.

No abstract available

B cell memory; T cell memory; anamnestic response; memory persistence; modeling; recall memory; vaccine.
2023 Abstract in Atti di convegno open access

Towards a digital twin for personalized diabetes prevention: the PRAESIIDIUM project

This contribution outlines current research aimed at developing models for personalized type 2 diabetes mellitus (T2D) prevention in the framework of the European project PRAESIIDIUM (Physics Informed Machine Learn-ing-Based Prediction and Reversion of Impaired Fasting Glucose Management) aimed at building a digital twin for preventing T2D in patients at risk. Specifically, the modelling approaches include both a multiscale, hybrid computational model of the human metaflammatory (metabolic and inflammatory) status, and data-driven models of the risk of developing T2D able to generate personalized recommendations for mitigating the individ-ual risk. The prediction algorithm will draw on a rich set of information for training, derived from prior clinical data, the individual's family history, and prospective clinical trials including clinical variables, wearable sensors, and a tracking mobile app (for diet, physical activity, and lifestyle). The models developed within the project will be the basis for building a platform for healthcare professionals and patients to estimate and monitor the indi-vidual risk of T2D in real time, thus potentially supporting personalized prevention and patient engagement.

multiscale modeling digital twins diabetes diabetes prevention machine learning physics informed machine learn multiscale models
2023 Abstract in rivista open access

A Molecular Dynamics Study of the Evolving Melt Front under Gravity

Giovanni Ciccotti ; Antonio Di Carlo ; Mauro Ferrario ; Daniela Mansutti

During melting under gravity in the presence of a horizontal thermal gradient, buoyancy-driven convection in the liquid phase affects significantly the evolution of the liquid-solid interface. Due to the obvious engineering interest in understanding and controlling melting processes, fluid dynamicists and applied mathematicians have spent many efforts to model and simulate them numerically. Their endeavors concentrated in the twenty-five years period between the publication of the paper by Brent, Voller &amp; Reid (1988) and that by Mansutti &amp; Bucchignani (2011). The former--and most of the following ones--adopted a phase-field model (where the interface is blurred into a smooth transition zone), while the latter was based on a Stefan-like model with sharp interface. With suitably chosen values of many ad-hoc material and numerical parameters, all of the above simulations were able to attain some agreement with their common benchmark, the melt fronts obtained experimentally by Gau &amp; Viskanta (1986) on a sample of gallium enclosed in a parallelepipedal box with one vertical wall heated. This left unresolved several fine issues, such as whether the elastic response of the solid phase plays a role in determining the shape of the liquid-solid interface.Here, for the first time, we tackle this problem at the atomistic level with a molec- ular dynamics approach. The advantage we gain is that a unique microscopic model describes all of the aggregation states of the molecules, and in particular the solid- liquid interface, without any further assumptions. The price we have to pay is that the hydrodynamical quantities of interest, computed out of the microscopic state using the Irwing &amp; Kirkwood (1950) prescriptions, need to be obtained under gravitational acceleration and thermal gradients much larger than those in real experiments.

molecular dynamics liquid/solid phase transtion constitutive equation convection displacement
2023 Abstract in rivista open access

Numerical Rock-Glacier Flow via the Pressure Method

Recent literature confirms the crucial influence of non-viscous deformations together with temperature impact on glacier and rock glacier flow numerical simulation. Along this line, supported by the successful test on a one-dimensional set-up developed by two of the author, we propose the numerical solution of a two-dimensional rock-glacier flow model based on an ice constitutive law of second grade differential type . The procedure adopted uses a 2nd order finite difference scheme and imposes the incompressibility constrain up to computer precision via the pressure method, ex- tended from newtonian computational fluid dynamics. The governing equations are solved in primitive variables with the advantage to avoid pre-/post-processing; splitted solution of the derived Poisson equation for pressure, source of undesired numerical mass unbalancing, is avoided as well. Numerical results will be shown.The financial support of Piano Nazionale Ricerca Antartide (project PNRA16-0012) is acknowledged.

numerical simulation, pressure method, rock-glacier flow