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2013 Articolo in rivista metadata only access

Functional strong law of large numbers for loads in a planar network model

2013 Articolo in rivista metadata only access

Point processes with Papangelou conditional intensity: from the Skorohod integral to the Dirichlet form

2013 Contributo in volume (Capitolo o Saggio) metadata only access

The lattice Boltzmann method as a general framework for blood flow modelling and simulations

S Melchionna ; G Pontrelli ; M Bernaschi ; M Bisson ; I Halliday ; TJ Spencer ; S Succi
2013 Curatela di monografia / trattato scientifico metadata only access

MASCOT 11 - Grid Gereration, Approximation and Visualization, IMACS Series in Computational and Applied Mathematics 17, 2013-ISSN 1098870X

2013 Prefazione/Postfazione metadata only access

MASCOT 11 Preface

2013 Contributo in Atti di convegno metadata only access

Land cover Mapping Capability of MULTISPECTRAL thermal data: THE TASI-600 case study

2013 Articolo in rivista metadata only access

Modelling the glycocalyx-endothelium-erythrocyte interaction in the microcirculation: a computational study

G Pontrelli ; I Halliday ; TJ Spencer ; CS Konig ; MW Collins
2013 Contributo in volume (Capitolo o Saggio) metadata only access

Drug release in biological tissues

F de Monte ; G Pontrelli ; S Becker
2013 Articolo in rivista metadata only access

On the lattice Boltzmann method as a computational framework for multiscale hemodynamics

G Pontrelli ; I Halliday ; S Melchionna ; T Spencer ; S Succi
2013 Articolo in rivista metadata only access

Local mass non-equilibrium dynamics in multi-layered porous media: application to the drug-eluting stents

2013 Contributo in Atti di convegno metadata only access

Modelling transdermal drug delivery through a two-layered system

2013 Monografia o trattato scientifico metadata only access

Complex Systems and Society - Modeling and Simulation

Ajmone Marsan Giulia ; Bellomo Nicola ; Tosin Andrea
2013 Articolo in rivista metadata only access

On the dynamics of social conflicts: Looking for the Black Swan

Bellomo Nicola ; Herrero Miguel Ángel ; Tosin Andrea

This paper deals with the modeling of social competition, possibly resulting in the onset of extreme conflicts. More precisely, we discuss models describing the interplay between individual competition for wealth distribution that, when coupled with political stances coming from support or opposition to a Government, may give rise to strongly self-enhanced effects. The latter may be thought of as the early stages of massive unpredictable events known as Black Swans, although no analysis of any fully-developed Black Swan is provided here. Our approach makes use of the framework of the kinetic theory for active particles, where nonlinear interactions among subjects are modeled according to game-theoretical principles. © American Institute of Mathematical Sciences.

Active particles Complexity Generalized kinetic theory Social systems Stochastic games
2013 Articolo in rivista metadata only access

A fully-discrete-state kinetic theory approach to modeling vehicular traffic

Fermo Luisa ; Tosin Andrea

This paper presents a new mathematical model of vehicular traffic, based on the methods of the generalized kinetic theory, in which the space of microscopic states (position and speed) of the vehicles is genuinely discrete. While in the recent literature discrete-velocity kinetic models of car traffic have already been successfully proposed, this is, to our knowledge, the first attempt to account for all aspects of the physical granularity of car flow within the formalism of the aforesaid mathematical theory. Thanks to a rich but handy structure, the resulting model allows one to easily implement and simulate various realistic scenarios giving rise to characteristic traffic phenomena of practical interest (e.g., queue formation due to roadwork or to a traffic light). Moreover, it is analytically tractable under quite general assumptions, whereby fundamental properties of the solutions can be rigorously proved. © 2013 Society for Industrial and Applied Mathematics.

Generalized kinetic theory Stochastic games Traffic granularity Vehicle interactions
2013 Articolo in rivista metadata only access

L-Proline Induces a Mesenchymal-like Invasive Program in Embryonic Stem Cells by Remodeling H3K9 and H3K36 Methylation

Metabolites are emerging as key mediators of crosstalk between metabolic flux, cellular signaling, and epigenetic regulation of cell fate. We found that the nonessential amino acid L-proline (L-Pro) acts as a signaling molecule that promotes the conversion of embryonic stem cells into mesenchymal-like, spindle-shaped, highly motile, invasive pluripotent stem cells. This embryonic-stem-cell-to-mesenchymal-like transition (esMT) is accompanied by a genome-wide remodeling of the H3K9 and H3K36 methylation status. Consistently, L-Pro-induced esMT is fully reversible either after L-Pro withdrawal or by addition of ascorbic acid (vitamin C), which in turn reduces H3K9 and H3K36 methylation, promoting a mesenchymal-like-to-embryonic-stem-cell transition (MesT). These findings suggest that L-Pro, which is produced by proteolytic remodeling of the extracellular matrix, may act as a microenvironmental cue to control stem cell behavior.

2013 Articolo in rivista metadata only access

Oil composition and genetic biodiversity of ancient and new olive (Olea europea L.) varieties and accessions of southern Italy

Cicatelli ; Aa ; Fortunati ; Tb ; De Feis ; Ic ; Castiglione ; Sa

The present study is focused on determining the olive oil fatty acid composition of ancient and recent varieties of the Campania region (Italy), but also on molecularly characterizing the most common cultivated varieties in the same region, together with olive trees of the garden of the University Campus of Salerno and of three olive groves of south Italy. Fatty acid methyl esters in the extra virgin oil derived olive fruits were determined, during three consecutive harvests, by gas chromatography. The statistical analysis on fatty acid composition was performed with the ffmanova package. The genetic biodiversity of the olive collection was estimated by using eight highly polymorphic microsatellite loci and calculating the most commonly used indexes. "Dice index" was employed to estimate the similarity level of the analysed olive samples, while the Structure software to infer their genetic structure. The fatty acid content of extra virgin olive oils, produced from the two olive groves in Campania, suggests that the composition is mainly determined by genotype and not by cultural practices or climatic conditions. Furthermore, the analysis conducted on the molecular data revealed the presence of 100 distinct genotypes and seven homonymies out of the 136 analysed trees. © 2013 Elsevier Ireland Ltd.

2013 Articolo in rivista metadata only access

A well-balanced scheme for kinetic models of chemotaxis derived from one-dimensional local forward-backward problems

Numerical approximation of one-dimensional kinetic models for directed motion of bacterial populations in response to a chemical gradient, usually called {\it chemotaxis}, is considered in the framework of well-balanced (WB) schemes. The validity of one-dimensional models have been shown to be relevant for the simulation of more general situations with symmetry in all but one direction along which appears the chemical attractant gradient. Two main categories are considered depending on whether or not the kinetic equation with specular boundary conditions admits non-constant macroscopic densities for large times. The WB schemes are endowed with the property of having zero artificial viscosity at steady-state; in particular they furnish numerical solutions for which the macroscopic flux vanishes, a feature that more conventional discretizations can miss. A class of equations which admit constant asymptotic states can be treated by a slight variation of the method of Case's elementary solutions originally developed for radiative transfer problems. More involved models which can display concentrations are handled through a different, but closely related, treatment of the tumbling term at the computational grid's interfaces. Both types of WB algorithms can be implemented efficiently relying on the Sherman-Morrison formula for computing interface values. Transient and stationary numerical results are displayed for several test-cases.

2013 Articolo in rivista metadata only access

Dynamics and rheology of vesicle suspensions in wall-bounded shear flow

A Lamura ; G Gompper

The dynamics and rheology of suspensions of fluid vesicles or red blood cells is investigated by a combination of molecular dynamics and mesoscale hydrodynamics simulations in two dimensions. The vesicle suspension is confined between two no-slip walls, which are driven externally to generate a shear flow with shear rate (gamma) over dot. The flow behavior is studied as a function of (gamma) over dot, the volume fraction of vesicles, and the viscosity contrast between inside and outside fluids. Results are obtained for the encounter and interactions of two vesicles, the intrinsic viscosity of the suspension, and the cell-free layer near the walls.

Membranes vesicles
2013 Contributo in Atti di convegno metadata only access

Comparing Habitat classification schemes for assessing landscape diversity

Kallimanis AS ; Dimopoulos P ; Tomaselli V ; Honrado J ; Lucas R ; Marangi C ; Blonda P

One of the core European Union environmental policies is the creation and monitoring of the Natura 2000 network of protected areas. This network has been explicitly established for the preservation of conservation priority habitat types and species. Still the concept of habitat is a key concept for ecologists that remains ill defined and is notoriously hard to quantify and measure. Several classification schemes have been put forward, but their relative strengths and weaknesses remain less well examined. In this study we analyzed 8 different Natura 2000 sites (3 Greek, 2 Italian, 2 Portuguese, 1 British). Our study sites reflect a variety of ecosystems, most of them are Mediterranean (7 of the 8) and most of them are wetlands (6 of the 8). In each site, we classified habitats according to 4 different classification schemes (Annex I of the Habitats Directive, Corine Biotopes, EUNIS and General Habitat categories). Also, we used three other widely used land cover classification schemes (namely Corine Land Cover, FAO Land Cover Classification System and IGBP DIS scheme). We found that the different schemes produced considerably different values of landscape diversity leading even to different ranking of the sites according to their diversity. Furthermore, when comparing the landscape composition among sites according to the different schemes, they led to different inferences. Our results imply that the classification scheme used for estimating habitat composition plays an important role for the monitoring of protected areas, perhaps more important than previously assumed.

2013 Contributo in Atti di convegno metadata only access

Comparison of Land Cover/Land Use and Habitat classification systems for Habitat mapping from space: strengths and weaknesses evidenced in Mediterranean sites of Natura 2000 network

Tomaselli V ; Dimopoulos P ; Marangi C ; Kallimanis AS ; Adamo M ; Tarantino C ; Panitsa M ; Terzi M ; Veronico G ; Lovergine F ; Nagendra H ; Lucas R ; Mairota P ; Mücher CA ; Blonda P

At a global level, protected sites have been established for the primary purpose of conserving biodiversity, with survey and monitoring of habitats undertaken largely within their boundaries. However, because of increasing human populations with greater access to resources, there is a need to now consider monitoring anthropic activities in the surrounding landscapes as pressures and disturbances are impacting on the functioning and biodiversity values of many protected sites. Earth Observation (EO) data acquired across a range of spatial and temporal scales offer new opportunities for monitoring biodiversity over varying time-scales, either through direct or indirect mapping of species or habitats. However, Land Cover (LC) and/or Land Use (LU), rather than habitat maps are generated in many national and international programs and, whilst the translation from one classification to the other is desirable, differences in definitions and criteria have so far limited the establishment of a unified approach. Focusing on both natural and non-natural environments associated with Natura 2000 sites in the Mediterranean, this paper considers the extent to which three common LC/LU taxonomies (CORINE, the Food and Agricultural Organisation (FAO) Land Cover Classification System (FAO-LCCS) and the IGBP) can be translated to habitat taxonomies with minimum use of additional environmental attributes and/or in situ data. A qualitative and quantitative analysis based on the Jaccard's index established the FAOLCCS as being the most useful taxonomy for harmonizing LC/LU maps with different legends and dealing with the complexity of habitat description and as a framework for translating EO-derived LC/LU to habitat categories. As demonstration, a habitat map of a wetland site is obtained through translation of the LCCS taxonomy.

habitat mapping