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2018 Articolo in rivista metadata only access

On the dynamics of an intraguild predator-prey model

Capone F ; Carfora MF ; De Luca R ; Torcicollo I

An intraguild predator-prey model with a carrying capacity proportional to the biotic resource, is generalized by introducing a Holling type II functional response. The longtime behaviour of solutions is analyzed and, in particular, absorbing sets in the phase space are determined. The existence of biologically meaningful equilibria (boundary and internal equilibria) has been investigated. Linear and nonlinear stability conditions for biologically meaningful equilibria are performed. Finally, numerical simulations on different regimes of coexistence and extinction of the involved populations have been shown.

Intraguild predation Stability Longtime behavior Holling type II functional response
2018 Articolo in rivista metadata only access

Influence of diffusion on the stability of a full Brusselator model

Capone F ; De Luca R ; Torcicollo I

The classic Brusselator model consists of four reactions in- volving six components A, B, D, E, X, Y. In a typical run, the final products D and E are removed instantly, while, the con- centrations of the reactants A and B are kept constant. Then, the classic Brusselator model consisting of two equations for the intermediate X and Y is obtained. When the component B is not considered constant, it is added to the mixture and the so-called full Brusselator model is considered. In this pa- per, the full Brusselator model is studied. In particular, the boundedness of solutions and the effect of diffusion on the linear stability is analyzed. Moreover, sufficient conditions ensuring that the unique steady state, unstable (stable) in the ODEs system, becomes stable (unstable) in presence of diffusion, are performed and a first nonlinear stability result is obtained.

Reaction-diffusion systems Brusselator model Stability Turing instability
2018 Prefazione/Postfazione metadata only access

On Applied Scientific Computing for Challenging Applications XIV - Preface

Prefazione al numero speciale della rivista dedicato agli articoli selezionati successivi al workshop MASCOT2015

computer science applied mathematics numerical analysis
2018 Abstract in Atti di convegno metadata only access

A continuum model for the coupled evolution of sea ice thickness and melt pond distribution

sea ice melt ponds mathematical modelling numerical simulation
2018 Curatela di numero monografico in rivista metadata only access

APPLIED SCIENTIFIC COMPUTING FOR CHALLENGING APPLICATIONS XIV (Special Issue)

volume speciale dedicato ad articoli selezionati e risultanti dal workshop MASCOT2015

Applied Scientific Computing Mathematical modelling Numerical Analysis
2018 Rapporto statistico metadata only access

Statistiche sul telelavoro biennio 2017/2018

Analisi dei dati relativi alle graduatorie del telelavoro biennio 2017/2018

Comitato Unico di Garanzia statistiche di genere telelavoro
2018 Abstract in Atti di convegno metadata only access

A HYPERBOLIC SYSTEM OF CHEMOTAXIS ON NETWORK MODELING PHYSARUM DYNAMICS

Many studies have shown that Physarum polycephalum slime mold is able to find the shortest path in a maze. Here we study this behavior in a network, using a hyperbolic model of chemotaxis [1]. Suitable transmission and boundary conditions at each node are considered to mimic the behavior of such an organism in the feeding process. Several numerical tests are presented for special network geometries to show the qualitative agreement between our model and the observed behavior of the mold.

networks physarum polycephalum shortest oath
2018 Articolo in rivista open access

Gamma-Convergence Analysis of a Generalized XY Model: Fractional Vortices and String Defects

Badal Rufat ; Cicalese Marco ; De Luca Lucia ; Ponsiglione Marcello

We propose and analyze a generalized two dimensional XY model, whose interaction potential has n weighted wells, describing corresponding symmetries of the system. As the lattice spacing vanishes, we derive by -convergence the discrete-to-continuum limit of this model. In the energy regime we deal with, the asymptotic ground states exhibit fractional vortices, connected by string defects. The -limit takes into account both contributions, through a renormalized energy, depending on the configuration of fractional vortices, and a surface energy, proportional to the length of the strings. Our model describes in a simple way several topological singularities arising in Physics and Materials Science. Among them, disclinations and string defects in liquid crystals, fractional vortices and domain walls in micromagnetics, partial dislocations and stacking faults in crystal plasticity.

XY spin systems Ginzburg-Landau Liquid Crystals Dislocations Calculus of Variations Gamma-convergence
2018 Articolo in rivista open access

Crystallization in Two Dimensions and a Discrete Gauss-Bonnet Theorem

De Luca L ; Friesecke G

We show that the emerging field of discrete differential geometry can be usefully brought to bear on crystallization problems. In particular, we give a simplified proof of the Heitmann-Radin crystallization theorem (Heitmann and Radin in J Stat Phys 22(3):281-287, 1980), which concerns a system of N identical atoms in two dimensions interacting via the idealized pair potential if , if , 0 if . This is done by endowing the bond graph of a general particle configuration with a suitable notion of discrete curvature, and appealing to a discrete Gauss-Bonnet theorem (Knill in Elem Math 67:1-7, 2012) which, as its continuous cousins, relates the sum/integral of the curvature to topological invariants. This leads to an exact geometric decomposition of the Heitmann-Radin energy into (i) a combinatorial bulk term, (ii) a combinatorial perimeter, (iii) a multiple of the Euler characteristic, and (iv) a natural topological energy contribution due to defects. An analogous exact geometric decomposition is also established for soft potentials such as the Lennard-Jones potential , where two additional contributions arise, (v) elastic energy and (vi) energy due to non-bonded interactions.

Crystallization Interaction potential Discrete differential geometry Energy minimization Gauss-Bonnet theorem
2018 Articolo in rivista metadata only access

New sets of Euler-type polynomials

Gabriella Bretti ; Pierpaolo Natalini ; Paolo Emilio Ricci

In recent papers, new sets of Sheffer and Brenke polynomials based on higher order Bell numbers have been studied, and several integer sequences related to them have been introduced. In the article other types of Sheffer polynomials are considered, by introducing two sets of Euler-type polynomials.

Sheffer polynomials combinatorial analysis bernoulli numbers Euler-type polynomials
2018 Articolo in rivista open access

Vaccination in the elderly: The challenge of immune changes with aging

Ciabattini Annalisa ; Nardini Christine ; Santoro Francesco ; Garagnani Paolo ; Franceschi Claudio ; Medaglini Donata

In this review we analyse the impact of age-associated factors such as inflammaging, immunosenescence and immunobiography on immune response to vaccination in the elderly, and we consider systems biology approaches as a mean for integrating a multitude of data in order to rationally design vaccination approaches specifically tailored for the elderly. The unprecedented increase of life expectancy challenges society to protect the elderly from morbidity and mortality making vaccination a crucial mean to safeguard this population. Indeed, infectious diseases, such as influenza and pneumonia, are among the top killers of elderly people in the world. Elderly individuals are more prone to severe infections and less responsive to vaccination prevention, due to immunosenescence combined with the progressive increase of a proinflammatory status characteristic of the aging process (inflammaging). These factors are responsible for most age-related diseases and correlate with poor response to vaccination. Therefore, it is of utmost interest to deepen the knowledge regarding the role of inflammaging in vaccination responsiveness to support the development of effective vaccination strategies designed for elderly.

Elderly vaccination Inflammaging Immunobiography Immunosenescence Vaccine adjuvants Systems biology
2018 Contributo in volume (Capitolo o Saggio) metadata only access

Multicomponent Lattice Boltzmann models for biological applications

Montessori A ; Halliday I ; Lauricella M ; Lishchuk S V ; Pontrelli G ; Spencer T J ; Succi S

The dynamics of deformable liquid-filled bodies (e.g., droplets, capsules, lipid vesicles) suspended in a fluid flow is a fascinating fundamental problem with increasing relevance for technological applications, for example, in drug delivery, or designing lab-on-chip devices. In the present chapter we review two main families of lattice Boltzmann models for multicomponent flows, their mechanical properties, and transport phenomena, with special focus on their application to biofluidic problems, such as the dynamics, merging, and breakup of microfluidic droplets and the motion of deformable membranes and vesicles under geometrical confinement.

Biofluidics Biological flows Lattice Boltzmann models Multicomponent flows Multiphase flows
2018 Contributo in volume (Capitolo o Saggio) metadata only access

Cyber Risk Management: a new challange for actuarial Mathematics

A specific kind of insurance that is emerging within the domain of cyber-systems is that of cyber-insurance. Cyber-insurance is the transfer of financial risk associated with network and computer incidents to a third party. Insurance companies are increasingly offering such policies, in particular in the USA, but also in Europe. The emerging trends in cyber insurance raise a number of unique challenges and force actuaries to reconsider how to think about underwriting, pricing and aggregation risk. Aim of this contribution is to offer a review of the recent literature on cyber risk management in the actuarial field. Moreover, basing on the most significant results in IT domain, we outline possible synergies between the two lines of research.

Risk Management Cyber Risk Cyber Insurance
2018 Contributo in Atti di convegno metadata only access

Who's Driving My Car? A Machine Learning based Approach to Driver Identification

Martinelli Fabio ; Mercaldo Francesco ; Nardone Vittoria ; Orlando Albina ; Santone Antonella

Despite the development of new technologies, in order to prevent the stealing of cars, the number of car thefts is sharply increasing. With the advent of electronics, new ways to steal cars were found. To avoid auto-theft attacks, in this paper we propose a machine leaning based method to silently e continuously profile the driver by analyzing built-in vehicle sensors. We evaluate the efficiency of the proposed method in driver identification using 10 different drivers. Results are promising, as a matter of fact we obtain a high precision and a recall evaluating a dataset containing data extracted from real vehicle.

Authentication Can Car Identification Machine Learning Obd
2018 Presentazione / Comunicazione non pubblicata (convegno, evento, webinar...) metadata only access

Gene regulatory network modeling of macrophage polarization supports the continuum hypothesis of phenotype differentiation states

Tieri P ; Palma A ; Castiglione F ; Jarrah A ; Cesareni G

Macrophages derived from monocyte precursors undergo specific polarization processes being influenced by the local tissue environment: classically-activated (M1) macrophages, showing a pro-inflammatory activity affecting effector cells in Th1 cellular immune responses; and alternatively-activated (M2) macrophages, with anti-inflammatory functions, involved in immunosuppression and tissue repair. At least three distinctive subsets of M2 macrophages, i.e. M2a, M2b and M2c, are characterized in the literature based on their eliciting molecular signals. The triggering and polarization of macrophages is attained through numerous, interweaved signaling pathways. To depict the logical relations among the genes involved in macrophage polarization, we utilized a computational modeling methodology, viz. Boolean modeling of gene regulation. We combined experimental data/knowledge from the literature to build a logical gene regulation network model driving macrophage polarization to M1, M2a, M2b and M2c phenotypes. Exploiting the GINsim software we studied the network dynamics under different settings and perturbations to comprehend how they affect cell polarization. Simulations of the network model, enacting the most significant biological conditions, showed consistency with the experimentally observed behaviour of in vivo macrophages. The model could properly replicate the polarization toward the four main phenotypes as well as to numerous hybrid phenotypes, known to be experimentally associated to physiological and pathological conditions. We speculate that shifts among different phenotypes in our model mimic the hypothetical continuum of macrophage polarization, with M1 and M2 being the poles of a continuous succession of states. Our simulations also suggest that anti-inflammatory macrophages are more resilient to shift to the pro-inflammatory phenotype.

mathemtical modeling immunology macrophage
2018 Contributo in Atti di convegno open access

Traffic Data: Exploratory Data Analysis with Apache Accumulo

The amount of traffic data collected by automatic number plate reading systems constantly incrseases. It is therefore important, for law enforcement agencies, to find convenient techniques and tools to analyze such data. In this paper we propose a scalable and fully automated procedure leveraging the Apache Accumulo technology that allows an effective importing and processing of traffic data. We discuss preliminary results obtained by using our application for the analysis of a dataset containing real traffic data provided by the Italian National Police. We believe the results described here can pave the way to further interesting research on the matter.

Apache Accumulo Exploratory Data Analysis Traffic Data
2018 Contributo in Atti di convegno open access

Unsupervised Classification of Routes and Plates from the Trap-2017 Dataset

This paper describes the efforts, pitfalls, and successes of applying unsupervised classification techniques to analyze the Trap-2017 dataset. Guided by the informative perspective on the nature of the dataset obtained through a set of specifically-written perl/bash scripts, we devised an automated clustering tool implemented in python upon openly-available scientific libraries. By applying our tool on the original raw data it is possibile to infer a set of trending behaviors for vehicles travelling over a route, yielding an instrument to classify both routes and plates. Our results show that addressing the main goal of the Trap-2017 initiative (``to identify itineraries that could imply a criminal intent'') is feasible even in the presence of an unlabelled and noisy dataset, provided that the unique characteristics of the problem are carefully considered. Albeit several optimizations for the tool are still under investigation, we believe that it may already pave the way to further research on the extraction of high-level travelling behaviors from gates transit records.

Traffic Data Clustering Unsupervised Classification
2017 Articolo in rivista metadata only access

Gravitational spin-orbit coupling in binary systems, post-Minkowskian approximation, and effective one-body theory

Bini Donato ; Damour Thibault

A novel approach for extracting gauge-invariant information about spin-orbit coupling in gravitationally interacting binary systems is introduced. This approach is based on the "scattering holonomy", i.e. the integration (from the infinite past to the infinite future) of the differential spin evolution along the two worldlines of a binary system in hyperboliclike motion. We apply this approach to the computation, at the first post-Minkowskian approximation (i.e. first order in G and all orders in v/c), of the values of the two gyrogravitomagnetic ratios describing spin-orbit coupling in the effective one-body formalism. These gyrogravitomagnetic ratios are found to tend to zero in the ultrarelativistic limit.

post-Minkowskian approximation effective one-body model
2017 Articolo in rivista open access

Existence of Isoperimetric Sets with Densities "Converging from Below" on RN

De Philippis G ; Franzina G ; Pratelli A

In this paper, we consider the isoperimetric problem in the space R with a density. Our result states that, if the density f is lower semi-continuous and converges to a limit a> 0 at infinity, with f<= a far from the origin, then isoperimetric sets exist for all volumes. Several known results or counterexamples show that the present result is essentially sharp. The special case of our result for radial and increasing densities positively answers a conjecture of Morgan and Pratelli (Ann Glob Anal Geom 43(4):331-365, 2013.

Isoperimetric problem Perimeter with density Existence of optimal sets
2017 Articolo in rivista restricted access

Hydrodynamic instabilities in active cholesteric liquid crystals

C A Whitfield ; T C Adhyapak ; A Tiribocchi ; G P Alexander ; D Marenduzzo ; S Ramaswamy

We describe the basic properties and consequences of introducing active stresses, with principal direction along the local director, in cholesteric liquid crystals. The helical ground state is found to be linearly unstable to extensile stresses, without threshold in the limit of infinite system size, whereas contractile stresses are hydrodynamically screened by the cholesteric elasticity to give a finite threshold. This is confirmed numerically and the non-linear consequences of instability, in both extensile and contractile cases, are studied. We also consider the stresses associated to defects in the cholesteric pitch (? lines) and show how the geometry near to the defect generates threshold-less flows reminiscent of those for defects in active nematics. At large extensile activity ? lines are spontaneously created and can form steady-state patterns sustained by constant active flows.

Active cholesteric liquid crystals Hydrodynamic instabilities Topological defects